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Redox labels and indicators based on transition metals and organic electroactive moieties for electrochemical nucleic acids sensing
- 1.0370535 - BFÚ 2012 RIV GB eng J - Journal Article
Fojta, Miroslav - Havran, Luděk - Pivoňková, Hana - Horáková Brázdilová, Petra - Hocek, Michal
Redox labels and indicators based on transition metals and organic electroactive moieties for electrochemical nucleic acids sensing.
Current Organic Chemistry. Roč. 15, č. 17 (2011), s. 2936-2949. ISSN 1385-2728. E-ISSN 1875-5348
R&D Projects: GA MŠMT(CZ) LC06035; GA MŠMT(CZ) LC512; GA AV ČR(CZ) IAA400040901; GA AV ČR(CZ) IAA400040903
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z40550506
Keywords : electrochemical methods * modified DNA * biosensor
Subject RIV: BO - Biophysics
Impact factor: 3.064, year: 2011
Electroactive indicators and labels are used in electrochemical nucleic acids sensing to improve selectivity and sensitivity of the biosensors and bioassays and to expand the palette of applicable electrode materials. Besides classical synthesis of modified nucleic acids, more facile and verstaile approaches have been introduced, based on either chemical modification of natural DNA components, or enzymatic incorporation of modified nucleotides.
Permanent Link: http://hdl.handle.net/11104/0204320
Number of the records: 1