Capillary electrophoresis applied to analysis and characterization of mono-N-acyl-2,6-diaminopimelic acid derivatives

0370091 - ÚOCHB 2012 CZ eng C - Conference Paper (international conference)
Vítovcová, M. - Hlaváček, Jan - Pícha, Jan - Vaněk, Václav - Jiráček, Jiří - Kašička, Václav
Capillary electrophoresis applied to analysis and characterization of mono-N-acyl-2,6-diaminopimelic acid derivatives.
Biologically Active Peptides. 12th Conference. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2011 - (Slaninová, J.), s. 159-162. Collection Symposium Series, 13. ISBN 978-80-86241-44-9.
[Biologically Active Peptides /12./. Praha (CZ), 27.04.2011-29.04.2011]
R&D Projects: GA ČR(CZ) GA203/08/1428; GA ČR(CZ) GA203/09/0675; GA AV ČR IAA400550614
Institutional research plan: CEZ:AV0Z40550506
Keywords : N-acyl-DAP derivatives * CZE and MEKC analysis * SDS micelles
Subject RIV: CC - Organic Chemistry

Capillary zone electrophoresis and micellar electrokinetic chromatography have been employed for determination of electrophoretic purity degree, limit of detection and limit of quantification of twelve mono-N­acylated derivatives of 2,6-diaminopimelic acid (DAP). In addition, the DAP derivatives were characterized by effective electrophoretic mobilities of their cationic and anionic forms in several classical and isoelectric buffer-based background electrolytes within a broad pH range 2.18 – 8.64.
Permanent Link: http://hdl.handle.net/11104/0203995