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Carbocyclic nucleosides with norbornane pseudosugar moiety locked in North conformation

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    0369987 - ÚOCHB 2012 GR eng A - Abstract
    Dejmek, Milan - Hřebabecký, Hubert - Šála, Michal - Nencka, Radim
    Carbocyclic nucleosides with norbornane pseudosugar moiety locked in North conformation.
    ESOC 2011. 17th European Symposium on Organic Chemistry. Crete: University of Crete, 2011. P2.121-P2.121.
    [ESOC 2011. European Symposium on Organic Chemistry /17./. 10.07.2011-15.07.2011, Crete]
    R&D Projects: GA MŠMT 1M0508
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : norbornane * conformationally locked nucleosides * carbocyclic nucleosides
    Subject RIV: CC - Organic Chemistry

    We report on synthesis of novel carbocylic nucleosides/tides locked in the North conformation. In order to lock the North conformation, norbornane substituted with base at C-3 position and with hydroxymethyl group at the bridgehead (C-1) position was used as the pseudosugar moiety.
    Permanent Link: http://hdl.handle.net/11104/0203915

     
     
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