Number of the records: 1
Generation of hydrogen peroxide in the developing rat heart: the role of elastin metabolism
- 1.0369506 - FGÚ 2012 RIV US eng J - Journal Article
Wilhelm, J. - Ošťádalová, Ivana - Vytášek, R. - Vajner, L.
Generation of hydrogen peroxide in the developing rat heart: the role of elastin metabolism.
Molecular and Cellular Biochemistry. Roč. 358, 1-2 (2011), s. 215-220. ISSN 0300-8177. E-ISSN 1573-4919
R&D Projects: GA MŠMT(CZ) 1M0510
Grant - others:GA ČR(CZ) GAP303/11/0298
Program: GA
Institutional research plan: CEZ:AV0Z50110509
Keywords : rat heart * ontogenetic development * hydrogen peroxide * elastin * fluorescence
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 2.057, year: 2011
The production of hydrogen peroxide (H2O2) during development (starting from day 21 after conception up to adulthood) of the rat heart was studied. H2O2, that modifies elastin, is produced by lysyl oxidase since day 4 up to day 15 only extracellularly, later on even intracellular production was observed. The specific inhibitor of lysyl oxadase abolished production of H2O2
Permanent Link: http://hdl.handle.net/11104/0203554
Number of the records: 1