Number of the records: 1
Common and distinct roles of juvenile hormone signaling genes in metamorphosis of holometabolous and hemimetabolous insect
- 1.0369386 - BC 2012 RIV US eng J - Journal Article
Konopová, Barbora - Smýkal, V. - Jindra, Marek
Common and distinct roles of juvenile hormone signaling genes in metamorphosis of holometabolous and hemimetabolous insect.
PLoS ONE. Roč. 6, č. 12 (2011), e28728. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GA204/07/1032; GA ČR(CZ) GD204/09/H058; GA AV ČR IAA500960906
Institutional research plan: CEZ:AV0Z50070508
Keywords : juvenile hormone
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.092, year: 2011
Juvenile hormone (JH) was so named for its capacity to block metamorphosis of larvae to adults. Only when larvae attain an appropriate stage, a halt of JH secretion permits metamorphosis. JH acts through its receptor, the Methoprene-tolerant (Met) protein, whose target gene Kr-h1 blocks metamorphosis. In this study we discovered that the same molecular mechanism of JH action operates in evolutionarily very distant insects with complete (holometaboly) and incomplete (hemimetaboly) metamorphosis, and is therefore universal to insects. The common role of Kr-h1 in suppressing metamorphosis supports hypotheses on common evolutionary origin of larval and pupal stages in the two types of metamorphosis.
Permanent Link: http://hdl.handle.net/11104/0203462
Number of the records: 1