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Biomaterials Applications for Nanomedicine

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    0367638 - ÚFCH JH 2012 RIV HR eng M - Monography Chapter
    Petrtýl, M. - Lísal, J. - Šenolt, L. - Bastl, Zdeněk - Kruliš, Zdeněk - Polanská, M. - Hulejová, H. - Černý, P. - Danešová, J.
    Hydrogel Scaffolds Contribute to the Ostogenesis and Chondrogenesis in the Small Osteochongral Defects.
    Biomaterials Applications for Nanomedicine. Rijeka: InTech, 2011 - (Pignatello, R.), s. 53-68. ISBN 978-953-307-661-4
    R&D Projects: GA ČR GA106/06/0761
    Institutional research plan: CEZ:AV0Z40400503; CEZ:AV0Z40500505
    Keywords : osteogenesis * chondrogenesis * physical chemistry
    Subject RIV: CF - Physical ; Theoretical Chemistry

    Hyaline cartilage shows only a limited response to self-repair (Hunter, 1743). Many people are stricken with degenerative osteochondral defects. Modern therapies of osteochondral defects are focused (for example) on the transplantation of osteochondral autografts, rushed spongiosa with collagen, chondrocytes and many others. The insertion of a crushed autologous bone graft has been reported as a possible therapy. However, the regenerative biomechanical (material) quality was less than 70% of healthy cartilage for fragments and controls (Kleemann et al., 2006). The transplantation of autologous osteochondral 3Dcylinders is one of several surgical therapies (Horas, 2003). During operations osteochondral defects are filled with material of a natural histological structure.
    Permanent Link: http://hdl.handle.net/11104/0202235

     
     
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