Antioxidant and prooxidant properties of flavonoids

0367572 - ÚEB 2012 RIV IT eng J - Journal Article
Procházková, Dagmar - Boušová, I. - Wilhelmová, Naděžda
Antioxidant and prooxidant properties of flavonoids.
Fitoterapia. Roč. 82, č. 4 (2011), s. 513-523. ISSN 0367-326X. E-ISSN 1873-6971
Grant - others:GA ČR GP524/09/P121
Program: GP
Institutional research plan: CEZ:AV0Z50380511
Keywords : Phenoxyl radical * Antioxidants * Prooxidants
Subject RIV: CE - Biochemistry
Impact factor: 1.848, year: 2011

The interest in possible health benefits of flavonoids has increased owing to their potent antioxidant and free radical scavenging activities observed in vitro. Nevertheless, the antioxidant efficacy of flavonoids in vivo is less documented and their prooxidant properties have been actually described in vivo. Due to their prooxidant properties, they are able to cause oxidative damage by reacting with various biomolecules, such as lipids, proteins and DNA. Hence, the aim of this review is to discuss both the antioxidant and prooxidant effects of flavonoids.
Permanent Link: http://hdl.handle.net/11104/0202202