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Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants

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    0365232 - FGÚ 2012 RIV US eng J - Journal Article
    Bačáková, Lucie - Filová, Elena - Pařízek, Martin - Ruml, T. - Švorčík, V.
    Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants.
    Biotechnology Advances. Roč. 29, č. 6 (2011), s. 739-767. ISSN 0734-9750. E-ISSN 1873-1899
    R&D Projects: GA ČR(CZ) GAP108/10/1106; GA ČR(CZ) GAP108/10/1858; GA AV ČR(CZ) KAN400480701; GA AV ČR(CZ) KAN101120701; GA AV ČR(CZ) IAAX00100902; GA AV ČR(CZ) IAA400320901
    Grant - others:GA AV ČR(CZ) KAN200100801
    Program: KA
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : biomaterial * surface patterning * bioartificial tissue * stem cells
    Subject RIV: EI - Biotechnology ; Bionics
    Impact factor: 9.646, year: 2011

    Artificial materials become more and more important cell carriers for tissue engineering and tissue replacemnet. Like natural ECM, they regulate the gene expression in cells, and as a consequence, the adhesion, viability, proliferation and differentiation of the cells. Cell attachment and spreading is strongly influenced by the physiochemical properties of the material surface, namely its chemical composition, surface energy, polarity, wettability, roughness, topography and mechanical properties
    Permanent Link: http://hdl.handle.net/11104/0200521

     
     
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