Applications of magnetic composite nanoparticles in medicine

0364160 - FZÚ 2012 CZ eng A - Abstract
Pollert, Emil
Applications of magnetic composite nanoparticles in medicine.
NANOCON 2010. Conference Proceedings. Ostrava: TANGER Ltd, 2010. s. 48. ISBN 978-80-87294-18-5.
[NANOCON 2010. International Conference /2./. 12.10.2010-14.10.2010, Olomouc]
R&D Projects: GA AV ČR KAN200200651
Institutional research plan: CEZ:AV0Z10100521
Keywords : composite magnetic nanoparticles * magnetic resonance imaging * magnetic fluid hyperthermia
Subject RIV: BM - Solid Matter Physics ; Magnetism

Synthesis of MNP for medical applications includes following points: Nanoparticles cores possessing magnetic properties corresponding to a given application should be developed. Surface properties of the cores that control interactions between particles (single or clustered objects), crucial for a stability of the suspensions and biocompability providing a stealth character of the particles and their long lifetime in the blood compartment should be adjusted. Active targeting employing molecules attached on the particles that bind by specific ligands with receptors at the surface of the targeted cells is desirable. The second part of the lecture is devoted to applications, namely magnetic resonance imaging as diagnostic method and magnetic fluid hyperthermia as therapeutic method.
Permanent Link: http://hdl.handle.net/11104/0199715