New Insights into the Lake Chad Basin Population Structure Revealed by High-Throughput Genotyping of Mitochondrial DNA Coding SNPs

0363370 - ARÚ 2012 RIV US eng J - Journal Article
Cerezo, M. - Černý, Viktor - Carracedo, Á. - Salas, A.
New Insights into the Lake Chad Basin Population Structure Revealed by High-Throughput Genotyping of Mitochondrial DNA Coding SNPs.
PLoS ONE. Roč. 6, č. 4 (2011), e18682. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GA206/08/1587
Institutional research plan: CEZ:AV0Z80020508
Keywords : population history * archaeogenetics * Lake Chad * SNP genotyping
Subject RIV: AC - Archeology, Anthropology, Ethnology
Impact factor: 4.092, year: 2011
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018682

This study is based on 230 SNP polymorphisms of mitochondrial DNA (mtSNP) in 542 samples from 12 populations located in Lake Chad Basin and evaluates populations of nomadic pastoralists and sedentary farmers. We provided thus much better phylogenetic resolution than previous studies of this geographic region. Using a Bayesian framework the nomadic populations showed negative growth which was not always correlated to their estimated effective population sizes. Nomads also showed lower diversity values than sedentary groups. Compared to sedentary population of the African Sahel, nomads thus showed signals of stronger genetic drift occurring in their ancestral populations. It is also interesting that the nomadic populations showed a higher North African influence than the sedentary populations of the Lake Chad Basin.
Permanent Link: http://hdl.handle.net/11104/0199304