Synthesis of 4-(het)aryl pyrimido[4,5-b]indole ribonucleosides

0361602 - ÚOCHB 2012 CZ eng C - Conference Paper (international conference)
Tichý, Michal - Hocek, Michal
Synthesis of 4-(het)aryl pyrimido[4,5-b]indole ribonucleosides.
Chemistry of Nucleic Acid Components. 15th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i., 2011 - (Hocek, M.), s. 475-476. Collection Symposium Series, 12. ISBN 978-80-86241-37-1.
[Chemistry of Nucleic Acid Components /15./. Český Krumlov (CZ), 05.06.2011-10.06.2011]
R&D Projects: GA MŠMT 1M0508; GA ČR GAP207/11/0344
Institutional research plan: CEZ:AV0Z40550506
Keywords : cytostatics * pyrimido[4,5-b]indole * ribonucleosides
Subject RIV: CC - Organic Chemistry

4,6-Dichloropyrimido[4,5-b]indole has been built-up from starting 2,4-dichloronitrobenzene in multigram scale and it has been used as key intermediate for synthesis of a series of 4-aryl or hetaryl ribonucleosides.
Permanent Link: http://hdl.handle.net/11104/0198884