Number of the records: 1
Enzymatic synthesis of ester prodrugs of DHPA and related compounds by lipases
- 1.0361135 - ÚOCHB 2012 CZ eng C - Conference Paper (international conference)
Blažek, Jiří - Kaiser, M. M. - Zarevúcka, Marie - Králová, B. - Krečmerová, Marcela
Enzymatic synthesis of ester prodrugs of DHPA and related compounds by lipases.
Chemistry of Nucleic Acid Components. 15th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i., 2011 - (Hocek, M.), s. 307-309. Collection Symposium Series, 12. ISBN 978-80-86241-37-1.
[Chemistry of Nucleic Acid Components /15./. Český Krumlov (CZ), 05.06.2011-10.06.2011]
R&D Projects: GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z40550506
Keywords : ester prodrugs * DHPA * lipases * transesterification * vinyl esters
Subject RIV: CC - Organic Chemistry
An enzymatic method was used for esterification of DHPA and related compounds with vinyl esters and catalyzed by different lipases in non-aqueous media (DMF). Esters of DHPA and other compounds could be synthesized and purified in satisfactory yields.
Permanent Link: http://hdl.handle.net/11104/0198529
Number of the records: 1