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Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone
- 1.0360252 - ÚBO 2012 RIV GB eng J - Journal Article
Wang, L. - Luzynski, K. - Pool, J. E. - Janoušek, V. - Dufková, Petra - Vyskočilová, Martina - Teeter, K. C. - Nachman, M. W. - Munclinger, P. - Macholán, Miloš - Piálek, Jaroslav - Tucker, P. K.
Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone.
Molecular Ecology. Roč. 20, č. 14 (2011), s. 2985-3000. ISSN 0962-1083. E-ISSN 1365-294X
R&D Projects: GA ČR GA206/08/0640
Grant - others:NSF(US) DEB0746560
Institutional research plan: CEZ:AV0Z60930519; CEZ:AV0Z50450515
Keywords : house mouse * hybrid zones * linkage disequilibrium * SNP markers
Subject RIV: EG - Zoology
Impact factor: 5.522, year: 2011
Theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes. However, direct observations of hybrid zone movement are difficult to make unless the zone is moving rapidly. Here, evidence for movement in the house mouse Mus musculus domesticus x M. m. musculus hybrid zone is provided using measures of LD and haplotype structure among neighbouring SNP markers from across the genome. Local populations of mice across two transects in Germany and the Czech Republic were sampled, and a total of 1301 mice were genotyped at 1401 markers from the nuclear genome. Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and, together with simulations, suggest hybrid zone movement because of either geography-dependent asymmetrical dispersal or selection favouring one subspecies over the other.
Permanent Link: http://hdl.handle.net/11104/0197848
Number of the records: 1