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NMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1
- 1.0359731 - FGÚ 2012 RIV US eng J - Journal Article
Lyukmanova, E. N. - Shenkarev, Z. O. - Shulepko, M. A. - Mineev, K. S. - D´Hoedt, D. - Kasheverov, I. E. - Filkin, S. Yu. - Krivolapova, A. P. - Janíčková, Helena - Doležal, Vladimír - Dolgikh, D. A. - Arseniev, A. S. - Bertrand, D. - Tsetlin, V.I. - Kirpichnikov, M. P.
NMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1.
Journal of Biological Chemistry. Roč. 286, č. 12 (2011), s. 10618-10627. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA305/09/0681
Institutional research plan: CEZ:AV0Z50110509
Keywords : NMR structure * nicotinic acetylcholine receptor * water-soluble domain
Subject RIV: FH - Neurology
Impact factor: 4.773, year: 2011
NMR and functional analysis both demonstrate that ws-LYNX1 is an appropriate model to shed light on the mechanism of LYNX1 action. Computer modeling, based on ws-LYNX1 NMR structure and AChBP x-ray structure, revealed a possible mode of ws-LYNX1 binding
Permanent Link: http://hdl.handle.net/11104/0197461
Number of the records: 1