The pleiotropic effect of WD-40 domain containing proteins on cellular differentiation and production of secondary metabolites in Streptomyces coelicolor M145

0357869 - MBÚ 2011 RIV SK eng O - Others
Ulrych, Aleš - Petříčková, Kateřina - Petříček, Miroslav - Vohradský, Jiří - Kofroňová, Olga - Benada, Oldřich - Branny, Pavel
The pleiotropic effect of WD-40 domain containing proteins on cellular differentiation and production of secondary metabolites in Streptomyces coelicolor M145.
KONGRES ČESKOSLOVENSKEJ SPOLOČNOSTI MIKROBIOLOGICKEJ /25./. Bratislava: Československá spoločnosť mikrobiologická, 2010. s. 206-206. ISBN 970-80-970477-8-8
Institutional research plan: CEZ:AV0Z50200510
Keywords : WD-40
Subject RIV: EE - Microbiology, Virology

WD-40 domains, also known as beta-transducin repeats, are highly conserved repeating amino acid units, which were found in a wide variety of eukaryotic proteins with different functions. In the late 1990s, the first WD-40 containing proteins have been identified in prokaryotes, however the knowledge about their function remained scarce. Streptomyces coelicolor is gram-positive bacterium with complicated morphological and physiological differentiation in the course of its life cycle. The genome of Streptomyces coelicolor contains 6 potential genes encoding proteins with WD-repeat motifs and it is thought that they could also play an important role in signal transduction
Permanent Link: http://hdl.handle.net/11104/0196049