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Lasiocepsin: Novel Antimicrobial Peptide from the Venom of Eusocial Bee Lasioglossum laticeps

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    0356823 - ÚOCHB 2011 DK eng C - Conference Paper (international conference)
    Monincová, Lenka - Slaninová, Jiřina - Fučík, Vladimír - Hovorka, Oldřich - Voburka, Zdeněk - Bednárová, Lucie - Maloň, Petr - Čeřovský, Václav
    Lasiocepsin: Novel Antimicrobial Peptide from the Venom of Eusocial Bee Lasioglossum laticeps.
    Peptides 2010: Tales of Peptides. Proceedings of the Thirty-First European Peptide Symposium. Copenhagen: European Peptide Society, 2010 - (Lebl, M.; Meldal, M.; Jensen, K.; Hoeg-Jensen, T.), s. 406-407. ISBN 0-9715560-5-9.
    [Peptides 2010: Tales of Peptides. Proceedings of the European Peptide Symposium /31./. Copenhagen (DK), 05.09.2010-09.09.2010]
    R&D Projects: GA ČR GA203/08/0536
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : antimicrobial peptide * bee venom * disulfide bridge * alpha -helical structures
    Subject RIV: CC - Organic Chemistry

    A novel antimicrobial peptide named lasiocepsin was isolated and characterized from the venom of eusocial bee Lasioglossum laticeps. Lasiocepsin, which contains 27 amino acid residues and 2disulfide bonds, and other two analogs differing in positions of disulfide bridges were synthesized. They were tested on antimicrobial and hemolytic activities and their secondary structure was measured by CD.
    Permanent Link: http://hdl.handle.net/11104/0195247

     
     
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