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Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced by Pseudallescheria boydii
- 1.0354251 - MBÚ 2011 RIV US eng J - Journal Article
Pavlásková, Kateřina - Nedvěd, Jan - Kuzma, Marek - Žabka, Martin - Šulc, Miroslav - Sklenář, Jan - Novák, Petr - Benada, Oldřich - Kofroňová, Olga - Hajduch, M. - Derrick, P.J. - Lemr, Karel - Jegorov, A. - Havlíček, Vladimír
Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced by Pseudallescheria boydii.
Journal of Natural Products. Roč. 73, č. 6 (2010), s. 1027-1032. ISSN 0163-3864. E-ISSN 1520-6025
R&D Projects: GA MŠMT LC07017
Institutional research plan: CEZ:AV0Z50200510
Keywords : EMERGING HUMAN PATHOGEN * SCEDOSPORIUM-APIOSPERMUM * ASPERGILLUS-FUMIGATUS
Subject RIV: EE - Microbiology, Virology
Impact factor: 2.872, year: 2010
Two Pseudallescheria boydii isolates have been identified as being producers of cyclic peptides. Five putative nonribosomal peptides with a unique structure, which have been named pseudacyclins, were characterized by nuclear magnetic resonance spectroscopy and mass spectrometry. The most abundant representative of the pseudacyclins was quantified also on fungal spores. The presence of these peptides on inhaled fungal spores creates the possibility for exploitation of pseudacyclins as early indicators of fungal infections caused by Pesudallescheria species
Permanent Link: http://hdl.handle.net/11104/0193298
Number of the records: 1