Number of the records: 1
Synthesis of deuterated neuroactive steroids
- 1.0351939 - ÚOCHB 2011 NO eng A - Abstract
Kapras, Vojtěch - Slavíčková, Alena - Chodounská, Hana - Valeš, Karel
Synthesis of deuterated neuroactive steroids.
IUPAC ICOS-18. The 18th International Conference on Organic Synthesis. Bergen, 2010.
[International Conference on Organic Synthesis /18./. 01.08.2010-06.08.2010, Bergen]
R&D Projects: GA ČR(CZ) GA203/08/1498; GA MZd(CZ) NS10528
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50110509
Keywords : neuroactive steroids * NMDA receptor * deuterium labeling * pharmacokinetics
Subject RIV: CC - Organic Chemistry
We have prepared trideuterated analogs of neuroactive steroids for pharmacokinetic tests. The described synthesis is effective and reaches products of high isotopic purity.
Permanent Link: http://hdl.handle.net/11104/0191567
Number of the records: 1