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Oxidative cleavage of 3beta-acetoxy-21-oxolup-18-en-28-oic acid by ruthenium tetroxide
- 1.0351597 - ÚOCHB 2011 RIV UZ eng J - Journal Article
Kvasnica, Miroslav - Spáčilová, Pavla - Buděšínský, Miloš - Hajdúch, M. - Sarek, J.
Oxidative cleavage of 3beta-acetoxy-21-oxolup-18-en-28-oic acid by ruthenium tetroxide.
Chemistry of Natural Compounds. Roč. 46, č. 4 (2010), s. 545-548. ISSN 0009-3130. E-ISSN 1573-8388
Grant - others:GA ČR(CZ) GA305/09/1216
Institutional research plan: CEZ:AV0Z40550506
Keywords : lupane triterpenoids * oxidation * ruthenium tetroxide * cleavage * decarboxylation
Subject RIV: CC - Organic Chemistry
Impact factor: 0.693, year: 2010
3Acetoxy-21-oxolup-18-en-28-oic acid was used for oxidative cleavage by ruthenium tetroxide in a biphasic system. Tricyclic and tetracyclic acids and their derivatives were prepared. All prepared compounds were tested on cytotoxic activity against CEM tumor cell. Some of them showed activity in low micromolar concentrations.
Permanent Link: http://hdl.handle.net/11104/0191314
Number of the records: 1