Methods of preparation of superparamagnetic nanoparticles based on iron oxides with modified surface and superparamagnetic nanoparticles obtained by such a method

0348526 - ÚMCH 2011 RIV DE eng P - Patent Document
Horák, Daniel - Syková, Eva - Babič, Michal - Jendelová, Pavla - Hájek, Milan
Methods of preparation of superparamagnetic nanoparticles based on iron oxides with modified surface and superparamagnetic nanoparticles obtained by such a method.
Munich: European Patent Office, 2010. Owner: Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i. Date of the patent acceptance: 08.09.2010. Patent Number: EP1991503
R&D Projects: GA ČR GA203/09/1242; GA AV ČR KAN201110651; GA MŠMT 1M0538
Grant - others:European Commission(XE) EC-FP6-DiMI LSHB-CT-2005-512146
Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50390512
Keywords : superparamagnetic * iron oxide * cell labeling
Subject RIV: CD - Macromolecular Chemistry
http://v3.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=1991503B1&KC=B1&FT=D&date=20100908&DB=EPODOC&locale=en_EP

Superparamagnetic nanoparticles (~ 10 nm) were developed based on iron oxides. Their surface was modified with mono-, di- or polysaccharides, amino acids or poly(amino acid)s or synthetic polymers based on (meth)acrylic acid and their derivatives. Nanoparticles are suitable for diagnostic and therapeutical applications including labeling of living cells. The invention provides a tool for monitoring the history and fate of cells transplanted into organism including their in vivo migration.
Permanent Link: http://hdl.handle.net/11104/0189045