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4-Deoxy-substrates for B-N-acetylhexosaminidases: How to make use of their loose specificity
- 1.0348173 - MBÚ 2011 RIV US eng J - Journal Article
Slámová, Kristýna - Gažák, Radek - Bojarová, Pavla - Kulik, Natallia - Ettrich, Rüdiger - Pelantová, Helena - Sedmera, Petr - Křen, Vladimír
4-Deoxy-substrates for B-N-acetylhexosaminidases: How to make use of their loose specificity.
Glycobiology. Roč. 20, č. 8 (2010), s. 1002-1009. ISSN 0959-6658. E-ISSN 1460-2423
R&D Projects: GA ČR GP203/09/P024; GA ČR GD305/09/H008; GA MŠMT(CZ) LC06010
Institutional research plan: CEZ:AV0Z50200510; CEZ:AV0Z60870520
Keywords : beta-N-acetylhexosaminidase * 4-deoxy-glycoside * enzymatic synthesis
Subject RIV: CC - Organic Chemistry
Impact factor: 3.791, year: 2010
B-N-Acetylhexosaminidases feature so-called wobbling specificity, which means that Theky cleave substrates both in gluco- and galacto- configurations, with the activity ratio depending on the enzyme source. Here we present the new finding that fungal B-N-acetylhexosaminidases are able to hydrolyze and transfer 4-deoxy-N-acetylhexosaminides with high yields
Permanent Link: http://hdl.handle.net/11104/0188770
Number of the records: 1