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Noise exposure during early development impairs the processing of sound intensity in adult rats
- 1.0345712 - ÚEM 2011 RIV GB eng J - Journal Article
Bureš, Zbyněk - Grécová, Jolana - Popelář, Jiří - Syka, Josef
Noise exposure during early development impairs the processing of sound intensity in adult rats.
European Journal of Neuroscience. Roč. 32, č. 1 (2010), s. 155-164. ISSN 0953-816X. E-ISSN 1460-9568
R&D Projects: GA ČR GA309/07/1336; GA MŠMT(CZ) LC554
Grant - others:GA ČR(CZ) GD309/08/H079
Institutional research plan: CEZ:AV0Z50390512
Keywords : auditory system * critical period * inferior colliculus
Subject RIV: FH - Neurology
Impact factor: 3.658, year: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0345712_01.pdf
The study demonstrates that exposure to intense noise at postnatal day 14 produced not only poorer frequency selectivity of neurons in the inferior colliculus (as reported previously by Grecova et al. (2009) Eur. J. Neurosci. 29, 1921–1930), but affected significantly the neuronal representation of sound intensity. Although the response thresholds were similar in the exposed and control rats, the neurons in the exposed animals had a longer first-spike latency, a narrower dynamic range, lower maximum response magnitudes and a steeper slope of the rate–intensity functions. The observed anomalies were confined to the mid- and high-frequency regions, whereas no significant changes were found in the low-frequency neurons.
Permanent Link: http://hdl.handle.net/11104/0186917
Number of the records: 1