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The relationship of polyethylene wear to particle size, distribution, and number: A possible factor explaining the risk of osteolysis after hip arthroplasty

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    0345073 - ÚMCH 2011 RIV US eng J - Journal Article
    Gallo, J. - Šlouf, Miroslav - Goodman, S. B.
    The relationship of polyethylene wear to particle size, distribution, and number: A possible factor explaining the risk of osteolysis after hip arthroplasty.
    Journal of Biomedical Materials Research. Part B. 94B, č. 1 (2010), s. 171-177. ISSN 1552-4973. E-ISSN 1552-4981
    R&D Projects: GA MŠMT 2B06096
    Institutional research plan: CEZ:AV0Z40500505
    Keywords : wear debris * polyethylene (UHMWPE) * periprosthetic osteolysis
    Subject RIV: CD - Macromolecular Chemistry
    Impact factor: 2.220, year: 2010

    The most critical factor in the development of periprosthetic osteolysis (OL) in total hip arthroplasty (THA) is the biological reaction to wear debris. We developed a computational algorithm for calculating the total number of PE particles for volumetric wear when particle size and distribution are known. We demonstrated that total number of PE wear particles strongly depends on their morphology (sizes, size distributions and shapes). These findings suggest that the risk for the development of OL in THA cannot be simply estimated from the volumetric wear alone.
    Permanent Link: http://hdl.handle.net/11104/0186427

     
     
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