Potencial of CE-MS for proteomics

0341742 - ÚIACH 2011 CZ eng A - Abstract
Hezinová, Věra - Simó, C. - Cifuentes, A. - Klepárník, Karel - Foret, František
Potencial of CE-MS for proteomics.
MSB 2010. Final Program and Book of Abstracts. 25 th International Symposium on Microscale BioSeparations. Brno: Ústav analytické chemie AV ČR, v. v. i, 2010 - (Foret, F.). s. 164. ISBN 978-80-254-6631-5.
[International Symposium on Microscale BioSeparations /25./. 21.03.2010-25.03.2010, Praha]
R&D Projects: GA AV ČR KAN400310651; GA AV ČR KJB400310709; GA ČR GA203/08/1680; GA ČR GA301/07/0490; GA MŠMT LC06023; GA MŠMT MEB060821
Institutional research plan: CEZ:AV0Z40310501
Keywords : capillary electrophoresis * mass spectrometry * proteomics
Subject RIV: CB - Analytical Chemistry, Separation

CE-MS become to be an important technique in proteomics because of its good separation efficiency and short analysis time. The only drawback is the lack of sensitivity, that should be reduced using various concentration methods like transient isotachophoresis, solid phase microextraction or by selection of appropriate CE-MS interface. The influence of these techniques on the sensitivity improvement has been studied on standard as well as real samples.
Permanent Link: http://hdl.handle.net/11104/0184633