Imaging mass spectrometry using desorption electrospray (DESI) coupled to a high resolution instrument

0341002 - MBÚ 2010 RIV AT eng A - Abstract
Vidová, Veronika - Volný, Michael - Pól, Jaroslav - Kobliha, Václav - Kruppa, G. - Lemr, Karel - Havlíček, Vladimír
Imaging mass spectrometry using desorption electrospray (DESI) coupled to a high resolution instrument.
Informal Meeting on Mass Spectrometry /27./. Retz: Asac, 2009. s. 53-53.
[Informal Meeting on Mass Spectrometry /27./. 03.05.2009-07.05.2009, Retz]
R&D Projects: GA MŠMT LC07017
Institutional research plan: CEZ:AV0Z50200510
Keywords : mass spectrometry
Subject RIV: EE - Microbiology, Virology

n DESI, an electrospray emitter aims at surface of interest and produces primary charged droplets that impact the surface and pick up the analyte (according to prevailing droplet pick up mechanism) that is transported into a mass spectrometer and ionized by processes similar to those that take place in the standard ESI. DESI is used mainly to analyze small to medium size polar molecules (e.g. drug metabolites, organic compounds, phospholipids, peptides) often in very complex environments and matrices (e.g. tissues, cell cultures)
Permanent Link: http://hdl.handle.net/11104/0184119