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Protein levels of CC chemokine ligand (CCL)15, CCL16 and macrophage stimulating protein in patients with sarcoidosis
- 1.0335206 - MBÚ 2010 RIV GB eng J - Journal Article
Arakelyan, A. - Kriegová, E. - Kubištová, I. - Mrázek, F. - Kverka, Miloslav - du Bois, R. M. - Kolek, V. - Petřek, M.
Protein levels of CC chemokine ligand (CCL)15, CCL16 and macrophage stimulating protein in patients with sarcoidosis.
Clinical and Experimental Immunology. Roč. 155, č. 3 (2009), s. 457-465. ISSN 0009-9104. E-ISSN 1365-2249
Institutional research plan: CEZ:AV0Z50200510
Keywords : bronchoalveolar lavage fluid * chemokines * cytokines
Subject RIV: EC - Immunology
Impact factor: 3.009, year: 2009
By comparing the cytokine spectra in broncho-alveolar fluid of two clinically distinct forms of sarcoidosis, we discovered four chemotactic factors that play an important role in the pathogenesis of sarcoidosis - CCL15, CCL16, MSP and MIF. Furthermore, by observing the disease course in the cohort of patients for two years, we found that CCL15 and MSP may affect disease course
Permanent Link: http://hdl.handle.net/11104/0179730
Number of the records: 1