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Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 6: 3D hydrogels with positive and negative surface charges and polyelectrolyte complexes in spinal cord injury repair
- 1.0332273 - ÚEM 2010 RIV GB eng J - Journal Article
Hejčl, Aleš - Lesný, Petr - Přádný, Martin - Šedý, Jiří - Zámečník, J. - Jendelová, Pavla - Michálek, Jiří - Syková, Eva
Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 6: 3D hydrogels with positive and negative surface charges and polyelectrolyte complexes in spinal cord injury repair.
Journal of Materials Science-Materials in Medicine. Roč. 20, č. 7 (2009), s. 1571-1577. ISSN 0957-4530. E-ISSN 1573-4838
R&D Projects: GA AV ČR IAA500390902
Grant - others:GA MŠk(CZ) 1M0538; GA MZd(CZ) 1A8697; EC FP6 project RESCUE(XE) LSHB-CT-2005-518233
Program: 1M
Institutional research plan: CEZ:AV0Z50390703; CEZ:AV0Z40500505
Keywords : transplantation * biomaterials * macroporous hydrogels
Subject RIV: FH - Neurology
Impact factor: 1.955, year: 2009
In this paper the authors evaluate 4 types of hydrogels based on 2-hydroxyethyl methacrylate, which differ in their surface charges. They find that hydrogels with surface charges improve cellular adhesion and axonal ingrowth compared to hydrogels with no surface charge. Further, hydrogels with positively charged surfaces improve the ingrowth of axons into the central parts of the bioimplants compared to hydrogels with negative charges.
Permanent Link: http://hdl.handle.net/11104/0177582
Number of the records: 1