Real-time X-Ray 2-D and 3-D micro-imaging of living animals with Medipix2 single photon counting detector

0329068 - BC 2010 US eng C - Conference Paper (international conference)
Frallicciardi, P. M. - Dammer, J. - Weyda, František - Jakůbek, J. - Vavřík, D. - Pospíšil, S.
Real-time X-Ray 2-D and 3-D micro-imaging of living animals with Medipix2 single photon counting detector.
2008 IEEE Nuclear Science Symposium Conference Record. New York: IEEE, 2009, s. 4760-4766. ISBN 978-1-4244-2714-7.
[Nuclear Science Symposium, Medical Imaging Conference and Room Temperature Semiconductor Detector Workshop /16./. Dresden (DE), 19.10.2008-25.10.2008]
R&D Projects: GA MŠMT 2B06005
Grant - others:GA MŠk(CZ) 1PO4LA211
Institutional research plan: CEZ:AV0Z50070508
Keywords : Medipix2
Subject RIV: EA - Cell Biology

In this work we present the study of applicability of a desktop size radiographic/tomographic X-ray system for real-time microscopy and micro-tomography in the fields of biology, entomology, botanic and medical imaging. The apparatus is made up of the single photon counting pixel silicon detector, Medipix2 (matrix of 256x256 square pixels of 55 μm pitch) and a microfocus X-ray tube with a minimum spot size of 5 μm and a tungsten anode. The system has been used for observations of time-dependent processes inside living and still biological and organic samples. Static and dynamic images of a parasite life cycle from the larva stage to pupa stage are presented here, as well as an in vivo computed tomography of the parasite living inside its host.
Permanent Link: http://hdl.handle.net/11104/0175202