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Molecular structure of purinergic P2X receptors and their expression in hypothalamus and pituitary

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    0321125 - FGÚ 2009 RIV CZ eng J - Journal Article
    Zemková, Hana - Balík, Aleš - Jindřichová, Marie - Vávra, Vojtěch
    Molecular structure of purinergic P2X receptors and their expression in hypothalamus and pituitary.
    [Molekulární struktura purinergních P2X receptorů a jejich exprese v hypothalamu a hypofýze.]
    Physiological Research. Roč. 57, Suppl.3 (2008), S23-S38. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA ČR(CZ) GA305/07/0681; GA AV ČR(CZ) IAA5011408; GA AV ČR(CZ) IAA500110702; GA MŠMT(CZ) LC554
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : purinergic P2X receptors * hypothalamus * pituitary
    Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
    Impact factor: 1.653, year: 2008

    Purinergic P2X receptors represent a novel structural type of ligand-gated ion channels activated by extracellular ATP. So far, seven P2X receptor subunits have been found in excitable as well as non-excitable tissues. In this work we summarized recent investigations about the structure of the P2X receptors, and expression and physiological roles played by the ATP and P2X receptors in the anterior pituitary and hypothalamus

    Purinergní P2X receptory představují nový strukturální typ ligandem aktivovaných iontových kanálů aktivovaných extracelulárním ATP. Dosud bylo nalezeno sedm podjednotek P2X receptrů v excitabilních i neexcitabilních tkáních. V tomto přehledu jsme shrnuli současné poznatky o struktuře P2X receptorů, jejich expresi a roli, kterou ATP a P2X receptory hrají v hypothalamu a hypofýze
    Permanent Link: http://hdl.handle.net/11104/0169792

     
     
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