Endothelial cells seeded and sheared on extracellular matrix proteins-coated vascular prostheses

0314784 - FGÚ 2009 NL eng A - Abstract
Chlupáč, Jaroslav - Filová, Elena - Riedel, Tomáš - Brynda, Eduard - Remy-Zolghadri, M. - Bareille, R. - Fernandez, P. - Daculsi, R. - Bordenave, L. - Bačáková, Lucie
Endothelial cells seeded and sheared on extracellular matrix proteins-coated vascular prostheses.
[Endotelové buňky vystavené steared stresu na cévních protézách potažených proteiny extracelulární matrix.]
8th World Biomaterials Congress. Amsterdam: Marathon International, 2008. ---.
[World Biomaterials Congress /8./. 28.05.2008-01.06.2008, Amsterdam]
R&D Projects: GA MŠMT(CZ) 1M0510; GA AV ČR(CZ) IAA5011301; GA AV ČR(CZ) IAA4050202; GA AV ČR(CZ) 1QS500110564
Grant - others:GA AV ČR(CZ) IAA400500507
Program: IA
Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z40500505
Keywords : spo2 * endothelial cells * stear stress * extracellular matrix prostheses
Subject RIV: EI - Biotechnology ; Bionics

We assessed adhesion and growth of endothelial cells on PET prosteses impregnated with collagen, laminin, fibrin and fibrin/fibronectin exposed to shear stress. The highest initial adhesion and growth were observed on prostheses coated with laminin and the highest cell retention under shear stress was on fibrin and fibrin/fibronectin

Hodnotili jsme adhezi a růst endotelových buněk na PET protézách impregnovaných kolagenem, lamininem, fibrinem a fibronektinem vystavených shear stresu. Nejvyšší adhezi a růst jsme pozorovali na protéze potažené lamininem a nejvyšší retence buněk byla v shear stresu na povrchu fibrinu a fibrinu/fibronektinu
Permanent Link: http://hdl.handle.net/11104/0165179