Toll-like receptor (TLR) 2,4 and CD14 expression and cytokine production by biopsy samples from IBD patients

0307569 - MBÚ 2008 RIV SIGLE JP eng C - Conference Paper (international conference)
Frolová, Lenka - Drastich, Pavel - Klimešová, Klára - Borovská, Dana - Rossmann, Pavel - Tlaskalová, Helena
Toll-like receptor (TLR) 2,4 and CD14 expression and cytokine production by biopsy samples from IBD patients.
[Toll-like receptory 2, 4 a CD14 exprese a cytokinová produkce střevní sliznice pacientů s IBD.]
International Congress of Mucosal Immunology. Tokyo: Elsevier, 2007, s. 299-299.
[International Congress of Mucosal Immunology. Tokyo (JP), 09.08.2007-12.08.2007]
R&D Projects: GA ČR GD310/03/H147
Institutional research plan: CEZ:AV0Z50200510
Keywords : cytokine, biopsy
Subject RIV: EC - Immunology

This study demonstrates that increased expression of TLR2, TLR4 and CD14 on intestinal mucosa cells and production of inflammatory cytokines are accompanying the development of IBD suggesting involvement of bacterial components in pathogenesis

Tato studie poukazuje na zvýšenou expresi TLR 2, 4 a CD14 na střevní sliznici a na produkci zánětlivých cytokinů, které se podílí na vzniku IBD za účasti bakteriálních komponentů v patogeneze těchto chorob
Permanent Link: http://hdl.handle.net/11104/0160292