Lactobacillus precolonization of SCID mouse mothers protect their offspring against the inflammation induced by dextran sulphate sodium treatment

0306935 - MBÚ 2008 RIV SIGLE AT eng C - Conference Paper (international conference)
Kozáková, Hana - Hudcovic, Tomáš - Hrnčíř, Tomáš - Štěpánková, Renata - Tlaskalová, Helena - Cukrowska, Božena
Lactobacillus precolonization of SCID mouse mothers protect their offspring against the inflammation induced by dextran sulphate sodium treatment.
[Prekolonizace SCID myší laktobacily od matek chrání mláďata proti zánětu vyvolanému dextransulfátem sodným.]
Congress of the European Crohn´s and Colitis Organisation. Innsbruck: Springer, 2007, s. 46-46.
[Congress of the European Crohn´s and Colitis Organisation. Innsbruck (AT), 01.03.2007-03.03.2007]
R&D Projects: GA MŠMT 2B06053; GA MŠMT 2B06155
Institutional research plan: CEZ:AV0Z50200510
Keywords : Intestinal inflammation
Subject RIV: EC - Immunology

The aim of the study was to show whether primary colonization of SCID mice with Lactobacillus rhamnosus affects the development of the experimental ulcerative colitis. Immunodeficient SCID mice were born to ex-germ-free mothers monocolonized with L. rhamnosus. L. rhamnosus prevented development of DSS-induced inflammation in conventional SCID mice

Cílem práce bylo zjistit, zda primární kolonizace SCID myší L. rhamnosus přirozenou cestou od matek je dostačující, aby zabránila vzniku DSS-enterokolitidy. Zjistili jsme, že tuto ochranu lze navodit
Permanent Link: http://hdl.handle.net/11104/0159828