Surface plasmon resonance biosensor based on integrated optical waveguides

0303728 - URE-Y 20000161 CH eng A - Abstract
Čtyroký, Jiří - Homola, Jiří - Brynda, Eduard - Skalský, Miroslav - Dostálek, Jakub - Schröfel, J.
Surface plasmon resonance biosensor based on integrated optical waveguides.
B.m.: Elsevier Science, 2000. 8th International Meeting on Chemical Sensors. Abstract book. s. 34
[International Meeting on Chemical Sensors IMCS /8./. 02.07.2000-05.07.2000, Basel]
R&D Projects: GA ČR GA102/99/0549; GA ČR GA102/00/1536
Institutional research plan: CEZ:AV0Z2067918
Keywords : surface plasmon resonance * optical sensors * integrated optics * biosensors * optical waveguides
Subject RIV: JB - Sensors, Measurment, Regulation

We report a sensor based on spectral interrogation of surface plasmon resonance (SPR) in an integrated optical waveguide-coupled surface plasmon resonance sensing device. We present theoretical analysis of the sensor structure, we demonstrate that the laboratory prototype of the sensor is capable of measuring refractive index changes smaller than 1.2x10.sup.-6.sup.. In conjuction with a-hCG the sensor is capable of detecting 2 ng/ml hCG present in 1.sup.o.sup./o bovine serum albumin solution.
Permanent Link: http://hdl.handle.net/11104/0113915