Number of the records: 1
Detection of neoplastic cells in blood of miniaturepigs with hereditary melanoma
- 1.0213328 - UZFG-Y 20010070 RIV CZ eng J - Journal Article
Pohlreich, P. - Stříbrná, J. - Kleibl, Z. - Horák, Vratislav - Klaudy, J.
Detection of neoplastic cells in blood of miniaturepigs with hereditary melanoma.
Veterinární medicína. Roč. 46, 7-8 (2001), s. 225, 230. ISSN 0375-8427. E-ISSN 1805-9392
R&D Projects: GA ČR GA524/01/0162; GA ČR GA523/98/0229; GA AV ČR KSK5011112
Keywords : melanoblastoma * circulating tumour cells
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.348, year: 2001
RT-PCR for tyrosine, a key enzyme of melanin biosynthesis, was utilised to analyse the peripheral blood of miniature pigs with malignant melanoma for the presence of tumour cells. Tyrosinase mRNA was detected in 62% of melanoma-bearing animals. It shows that tumour dissemination in advanced porcine melanoma can be ascertained by this way similarly as in human patients.
Permanent Link: http://hdl.handle.net/11104/0108866
Number of the records: 1