Single-Voxel Short-Echo Time Proton Spectroscopy of Human Brain with Standard Surface Coils

0205352 - UPT-D 20000131 RIV US eng C - Conference Paper (international conference)
Mlynárik, V. - Gruber, S. - Starčuk, Zenon - Starčuk jr., Zenon - Roden, M. - Moser, E.
Single-Voxel Short-Echo Time Proton Spectroscopy of Human Brain with Standard Surface Coils.
Proceedings of 8th Scientific Meeting and Exhibition Magnetic Resonance in Medicine. Denver: ISMRM, 2000, s. 1857.
[ISMRM /8./ - Scientific Meeting and Exhibition. Denver (US), 01.04.2000-07.04.2000]
Institutional research plan: CEZ:AV0Z2065902
Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

In spite of the development of multi-voxel spectroscopy techniques, proton single voxel MR spectroscopy is still the method of choice in many clinical examinations of the human brain. For measuring spectra from the brain cortex, surface coils can be preferably used due to their higher sensitivity and lower power deposition compared to volume coils. However, surface coils used as a transmitter are limited by the inhomogeneous B1 field produced. This as a serious complication for pulse sequences that require well defined flip angles, especially for suppressing the strong water signal. Only a few reports on the measurement of proton spectra from the human brain using surface coils as transmitters appeared in the literature. In these papers, either a specially designed coil with a region of relatively homogenous B1 field was constructed or a combination of specific hardware and software was used for outer volume amd water suppression, with the aim of spectral editting of GABA. To our best knowledge, this is the first report on a single voxel STEAM spectrum of human brain produced solely by a standard surface coil. Efficient water suppression was achieved by a modification of the method originally proposed by de Graaf and Nicolay.
Permanent Link: http://hdl.handle.net/11104/0100966