Robust, Efficient, and Flexible Water Suppression for In Vivo Proton MRS

0205337 - UPT-D 20000116 RIV PL eng C - Conference Paper (international conference)
Starčuk jr., Zenon - Starčuk, Zenon - Mlynárik, V. - Gruber, S. - Horký, Jaroslav - Moser, E.
Robust, Efficient, and Flexible Water Suppression for In Vivo Proton MRS.
2nd Krakow-Winnipeg Workshop on Biomedical Application of MRI and MRS. Krakow: Komitet Badaň Naukovych, 2000, s. 36.
[Biomedical Application of MRI and MRS /2./ - Krakow-Winnipeg Workshop. Krakow (PL), 01.10.2000-04.10.2000]
Institutional research plan: CEZ:AV0Z2065902
Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

Quantitation of in vivo ¹H MR spectra can be severely hampered by insuffisient suppresion of water signals, which may be related to the dispersion of water T₁ relaxation times and to B₁ field inhomogenity, especially if a transmit/receive surface coil is used. Variable flip-angle methods WET and VAPOR provide excellent T₁ insensitivity and low SAR, but B₁ sensitivity is still a problem with simple surface coils. Outer volume suppresion (OVS) may be desirable if considerable SAR increase is acceptable. SWAMP, flipping the water magnetization by transition region of adiabatic inversion pulses, achieves excellent B1 insensitivity, but at the expense of much higher SAR, and either the interpulse delays are too short for sufficient gradient crushers or OVS, or its efficiency suffers from T₁ sensitivity. we propose a superior type of methods, related to both mentioned classes.
Permanent Link: http://hdl.handle.net/11104/0100951