Very Short Echo Time Proton MR Spectroscopy of Human Brain With a Standard Transmit/Receive Surface Coil

0205326 - UPT-D 20000105 RIV US eng J - Journal Article
Mlynárik, V. - Gruber, S. - Starčuk, Zenon - Starčuk jr., Zenon - Moser, E.
Very Short Echo Time Proton MR Spectroscopy of Human Brain With a Standard Transmit/Receive Surface Coil.
Magnetic Resonance in Medicine. Roč. 44, č. 6 (2000), s. 964-967. ISSN 0740-3194. E-ISSN 1522-2594
R&D Projects: GA AV ČR IAA4065901
Grant - others:AKTION(AT) 24p15
Institutional research plan: CEZ:AV0Z2065902
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 3.121, year: 2000

A method for localised proton spectroscopy of the human brain is proposed which can be used with a standard transmit/receive planar surface coil producing an inhomogeneous RF field. Water suppresion is accomplished by a train of full passage adiabatic pulses with optimized frequencies and delays, which account for variation in the water resonance frequency and the spin-lattice relaxation time. The robust method requires minimal pulse calibration and provides high-quality spectra even at very short echo times and in the absence of outer volume saturation and, therefore, is well suited for clinical in vivo spectroscopy. The performance of the method is demonstrated on a test object and on MR spectra from the human brain a 3 T.
Permanent Link: http://hdl.handle.net/11104/0100940