0194800 - UOCHB-X 20030106 RIV CZ eng J - Journal Article
Čapek, Petr - Otmar, Miroslav - Masojídková, Milena - Votruba, Ivan - Holý, Antonín
A facile synthesis of 9-deaza analogue of olomoucine.
Collection of Czechoslovak Chemical Communications. Roč. 68, č. 4 (2003), s. 779-791. ISSN 0010-0765
R&D Projects: GA MŠMT OC D13.20
Institutional research plan: CEZ:AV0Z4055905
Keywords : purines * antitumor activity * cytostatics
Subject RIV: CC - Organic Chemistry
Impact factor: 1.041, year: 2003

9-Deaza analogue of cytokinin olomoucine was synthesized without showing any considerable cytostatic activity. Antiproliferative activity on CCRF-CEM cells (IC₅₀=13.3ćM) was found in 6-(benzylamino)-9-deazapurine.

Permanent Link: http://hdl.handle.net/11104/0090471