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An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed Cross-coupling reactions of 2,6-dichloropurines

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    0194771 - UOCHB-X 20030077 RIV US eng J - Journal Article
    Hocek, Michal - Dvořáková, H.
    An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed Cross-coupling reactions of 2,6-dichloropurines.
    Journal of Organic Chemistry. Roč. 68, č. 14 (2003), s. 5773-5776. ISSN 0022-3263. E-ISSN 1520-6904
    R&D Projects: GA AV ČR IAB4055201
    Institutional research plan: CEZ:AV0Z4055905
    Keywords : purines * nucleosides * cross-coupling
    Subject RIV: CC - Organic Chemistry
    Impact factor: 3.297, year: 2003

    Fe-catalyzed cross-coupling reactions of 9-substituted or protected 2,6-dichloropurines with 1 equiv of methylmagnesium chloride gave regioselectively 2-chloro-6-methylpurines in good yields.
    Permanent Link: http://hdl.handle.net/11104/0090442

     
     

Number of the records: 1  

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