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An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed Cross-coupling reactions of 2,6-dichloropurines
- 1.0194771 - UOCHB-X 20030077 RIV US eng J - Journal Article
Hocek, Michal - Dvořáková, H.
An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed Cross-coupling reactions of 2,6-dichloropurines.
Journal of Organic Chemistry. Roč. 68, č. 14 (2003), s. 5773-5776. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA AV ČR IAB4055201
Institutional research plan: CEZ:AV0Z4055905
Keywords : purines * nucleosides * cross-coupling
Subject RIV: CC - Organic Chemistry
Impact factor: 3.297, year: 2003
Fe-catalyzed cross-coupling reactions of 9-substituted or protected 2,6-dichloropurines with 1 equiv of methylmagnesium chloride gave regioselectively 2-chloro-6-methylpurines in good yields.
Permanent Link: http://hdl.handle.net/11104/0090442
Number of the records: 1