[2+2+2]-Co-cyclotrimerization 6-alkynylpurines with diynes: a method for preparation of 6-arylpurines

0194768 - UOCHB-X 20030073 RIV GB eng J - Journal Article
Turek, P. - Kotora, M. - Hocek, Michal - Císařová, I.
[2+2+2]-Co-cyclotrimerization 6-alkynylpurines with diynes: a method for preparation of 6-arylpurines.
Tetrahedron Letters. Roč. 44, č. 4 (2003), s. 785-788. ISSN 0040-4039. E-ISSN 1873-3581
R&D Projects: GA ČR GA203/01/0863; GA ČR GA203/00/0036; GA ČR GA203/03/0035
Institutional research plan: CEZ:AV0Z4055905
Keywords : purines * nucleosides * cycloadditions
Subject RIV: CC - Organic Chemistry
Impact factor: 2.326, year: 2003

A novel approach to 6-alkynylpurines based on [2+2+2]-co-cyclotrimerization of 6-alkynylpurines with various alfa, omega-diynes is described. Co-cyclotrimerization is catalyzed by Ni- and Co-phosphine catalysts and their choice depends on the substitution pattern of the both reactants.
Permanent Link: http://hdl.handle.net/11104/0090439