0194121 - UOCHB-X 20010204 RIV CZ eng J - Journal Article
Hocek, Michal - Holý, Antonín - Votruba, Ivan - Dvořáková, H.
Cytostatic 6-arylpurine nucleosides III. Synthesis and structure-activity relationship study in cytostatic activity of 6-aryl-, 6-hetaryl- and 6-benzylpurine ribonucleosides.
Collection of Czechoslovak Chemical Communications. Roč. 66, č. 3 (2001), s. 483-499. ISSN 0010-0765
R&D Projects: GA ČR GV203/96/K001; GA ČR GA203/00/0036
Institutional research plan: CEZ:AV0Z4055905
Keywords : purines * nucleosides
Subject RIV: CC - Organic Chemistry
Impact factor: 0.778, year: 2001

A series of 6-aryl, 6-hetaryl and 6-benzylpurine ribonucleosides has been prepared by Pd-catalyzed cross-coupling reactions of 6-chloro-9-(2,3,5-tri-.I.O./I.-acetyl-á-D-ribofuranosyl)-purine with arylboronic acid, hetarylzinc halides, hetarylstannanes or benzylzinc halides followed by deprotection.
Permanent Link: http://hdl.handle.net/11104/0089812