New monoclonal antibody to human apolipoprotein J

0191639 - UMG-J 20033149 RIV CZ eng J - Journal Article
Čapková, Jana - Geussová, Gizela - Pěknicová, Jana
New monoclonal antibody to human apolipoprotein J.
Folia Biologica. Roč. 2002, č. 48 (2002), s. 40-42. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA ČR GV524/96/K162
Grant - others:NFDK-MAOB(XE) 1985-NFDK-MAOB
Institutional research plan: CEZ:AV0Z5052915
Keywords : apo J * human spermatoza * monoclonal antibody
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.615, year: 2002

Apolipoprozein J (apoJ) is a 70 kDa glycoprotein associated with higf-density lipoproteins (HDL) in human plasma (de Silva et al., 1990a). HDL transport more than 80% of the plasma cholesterol from extrahepatic tussues to the liver for excretion (Glomset, 1968). ApoJ is also secondaeily incorporated into the sperm membrane, as sperm travel trought the male reproductive tract, and belong to the spoer-coating proteins. among monoclonal antibodies against human sperm proteins that we generted, a monoclonal antibody that specifically recognezed apoJ was found. The monoclonal antibody was designated Hs-3.
Permanent Link: http://hdl.handle.net/11104/0087377