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Prophylactic, therapeutic and anti-metastatic effects of BMDC and DC lines in mice carrying HPV16-associated tumours

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    0191583 - UMG-J 20033050 RIV GR eng J - Journal Article
    Mendoza, Luis - Bubeník, Jan - Šímová, Jana - Jandlová, Táňa - Vonka, V. - Mikyšková, Romana
    Prophylactic, therapeutic and anti-metastatic effects of BMDC and DC lines in mice carrying HPV16-associated tumours.
    International Journal of Oncology. Roč. 23, č. 1 (2003), s. 243-247. ISSN 1019-6439. E-ISSN 1791-2423
    R&D Projects: GA MZd NC7148; GA ČR GA301/01/0985; GA AV ČR IAA5052203
    Grant - others:Liga proti rakovině(CZ) -
    Institutional research plan: CEZ:AV0Z5052915
    Keywords : HPV 16 * dendritic cells * residual tumour disease
    Subject RIV: FD - Oncology ; Hematology
    Impact factor: 2.536, year: 2003

    Subcutaneous transplantation of oncogenic, moderately immunogenic MK16 cells produced progressively growing neoplasms spontaneously metastasizing to lungs. Prophylactic administration of bone-marrow derived dendritic cells as well as dendritic cell lines DC2.4 and JAWS II at the site of subsequent MK16 tumour transplants inhibited tumour growth and reduced the number of lung metastases.
    Permanent Link: http://hdl.handle.net/11104/0087325

     
     

Number of the records: 1  

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