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Prophylactic, therapeutic and anti-metastatic effects of BMDC and DC lines in mice carrying HPV16-associated tumours
- 1.0191583 - UMG-J 20033050 RIV GR eng J - Journal Article
Mendoza, Luis - Bubeník, Jan - Šímová, Jana - Jandlová, Táňa - Vonka, V. - Mikyšková, Romana
Prophylactic, therapeutic and anti-metastatic effects of BMDC and DC lines in mice carrying HPV16-associated tumours.
International Journal of Oncology. Roč. 23, č. 1 (2003), s. 243-247. ISSN 1019-6439. E-ISSN 1791-2423
R&D Projects: GA MZd NC7148; GA ČR GA301/01/0985; GA AV ČR IAA5052203
Grant - others:Liga proti rakovině(CZ) -
Institutional research plan: CEZ:AV0Z5052915
Keywords : HPV 16 * dendritic cells * residual tumour disease
Subject RIV: FD - Oncology ; Hematology
Impact factor: 2.536, year: 2003
Subcutaneous transplantation of oncogenic, moderately immunogenic MK16 cells produced progressively growing neoplasms spontaneously metastasizing to lungs. Prophylactic administration of bone-marrow derived dendritic cells as well as dendritic cell lines DC2.4 and JAWS II at the site of subsequent MK16 tumour transplants inhibited tumour growth and reduced the number of lung metastases.
Permanent Link: http://hdl.handle.net/11104/0087325
Number of the records: 1