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Caveolae are involved in the trafficing of mouse polyomavirus virions and artificial VP1 pseudocapsids toward cell nuclei
- 1.0191323 - UMG-J 20010393 RIV US eng J - Journal Article
Richterová, Z. - Liebl, D. - Horák, M. - Palková, Z. - Štokrová, Jitka - Hozák, Pavel - Korb, Jan - Forstová, J.
Caveolae are involved in the trafficing of mouse polyomavirus virions and artificial VP1 pseudocapsids toward cell nuclei.
Journal of Virology. Roč. 75, č. 22 (2001), s. 10880-10891. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA ČR GA204/00/0271; GA MŠMT VS96130
Grant - others:HHMI(US) 75195-540501
Keywords : polyomavirus internalization * VP1 pseudocapsids * caveolae
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.622, year: 2001
Colocalization of VP1 with caveolin-1 was observed during viral particle movement from the plasma membrane throughout the cytoplasm to the perinuclear area. Microfilaments decorated by the VP1 immunofluorescent signal could be seen as concentric curves, apparently along membrane structures that probably represent endoplasmic reticulum. However, the vast majority of VP1 pseudocapsids did not enter the nuclei.
Permanent Link: http://hdl.handle.net/11104/0087078
Number of the records: 1