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Phenotype, Immunological Reactivity and Cytokine Production Profile of Peyer`s Patch Cells from Mice Immunized Orally with Allogeneic Cells
- 1.0190946 - UMG-J 20000042 RIV CZ eng J - Journal Article
Frič, Jan - Krulová, Magdalena - Zajícová, Alena - Holáň, Vladimír
Phenotype, Immunological Reactivity and Cytokine Production Profile of Peyer`s Patch Cells from Mice Immunized Orally with Allogeneic Cells.
Folia Biologica. Roč. 46, č. 3 (2000), s. 119-125. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA ČR GA310/99/0360; GA ČR GA310/97/1261; GA ČR GA310/99/D044; GA MZd IZ3964; GA MŠMT VS97099; GA MŠMT ME 300
Grant - others:NATO(BE) CRG.LG972853
Institutional research plan: CEZ:AV0Z5052915
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.351, year: 2000
Changes in immunological reactivity of mice after oral administration of allogeneic cells have been studied. It wasshown that oral immunization specifically inhibits the immune system and that it is possible to demonstrate these changes already at the level of Peyer`s patch cells. Using the ELISA test and RT-PCR, increased production of Th1 cytokines has been shown. This immunization was demonstrated systemically by increased resistance to the growth of allogeneic tumors.
Permanent Link: http://hdl.handle.net/11104/0086708
Number of the records: 1