Tissue-Engineered Skin in the Treatment of Vitiligo Lesions

0190943 - UMG-J 20000039 RIV CZ eng J - Journal Article
Arenberger, P. - Brož, L. - Veselý, Pavel - Havlíčková, B. - Matoušková, Eva
Tissue-Engineered Skin in the Treatment of Vitiligo Lesions.
Folia Biologica. Roč. 46, č. 4 (2000), s. 157-160. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA MZd IZ4368; GA MZd NK6126
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.351, year: 2000

In five vitiligo patients, autologous epidermal cells were obtained from pigmented thin skin biopsies. Thecells were cultured on a dried cell-free porcine dermis with the 3T3 feeder layer technique. Melanocytes wereregularly dispersed in confluent keratinocyte cultures. The epidermal layer was directly applied into the dermabraded vitiligo lesion with porcine dermis covering the lesion. The pigmentation started to be visible 4-6 weeks after grafting. UVA irradiation enhanced the treatmentsuccess up to 100
Permanent Link: http://hdl.handle.net/11104/0086705