Number of the records: 1
Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells
- 1.0190933 - UMG-J 20000029 RIV NL eng J - Journal Article
Zíková, Martina - Sulimenko, Vadym - Dráber, Pavel - Dráberová, Eduarda
Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells.
FEBS Letters. Roč. 473, č. 1 (2000), s. 19-23. ISSN 0014-5793. E-ISSN 1873-3468
R&D Projects: GA ČR GV312/96/K205; GA ČR GA204/98/1054; GA AV ČR KSK2038602
Institutional research plan: CEZ:AV0Z5052915
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.440, year: 2000
Expression of the MA-01 antigen, a thermolabile 210 kDa microtubule-interacting protein, was analysed during neuronal differentiation of P19 embryonal carcinoma cells. The level of MA-01 expression increased approximately ten times during 15 days. The increase started after 2 days of incubation with retinoaic acid and preceded the appearance of neuron-specific tubulin betaIII and neurofilaments. These data indicate that enhanced expression of MA-01 antigen is one of the earliest events occurring in P19 cells during neuronal differentiation.
Permanent Link: http://hdl.handle.net/11104/0086695
Number of the records: 1