HPMA copolymers with pH-controlled release of doxorubicin. In vitro cytotoxicity and in vivo antitumor activity

0189050 - UMCH-V 20033002 RIV NL eng J - Journal Article
Ulbrich, Karel - Etrych, Tomáš - Chytil, Petr - Jelínková, Markéta - Říhová, Blanka
HPMA copolymers with pH-controlled release of doxorubicin. In vitro cytotoxicity and in vivo antitumor activity.
Journal of Controlled Release. Roč. 87, 1-3 (2003), s. 33-47. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR GA305/02/1425; GA ČR GA305/99/D051; GA AV ČR IBS5020101; GA AV ČR IAA4050201
Institutional research plan: CEZ:AV0Z5020903; CEZ:AV0Z4050913
Keywords : HPMA copolymers * drug carriers * doxorubicin
Subject RIV: CE - Biochemistry
Impact factor: 3.298, year: 2003

Data on the synthesis, physicochemical characterisation and in vitro and in vivo biological properties of the new, nontargeted or antibody-targeted polymer-doxorubicin conjugates designed as anticancer drugs are presented.
Permanent Link: http://hdl.handle.net/11104/0084910